Erik R Nelson Selected Research

27-hydroxycholesterol

1/2022	Our evolving understanding of how 27-hydroxycholesterol influences cancer.
1/2021	The Cholesterol Metabolite 27HC Increases Secretion of Extracellular Vesicles Which Promote Breast Cancer Progression.
11/2020	27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression.
1/2019	Host CYP27A1 expression is essential for ovarian cancer progression.
1/2018	The significance of cholesterol and its metabolite, 27-hydroxycholesterol in breast cancer.
10/2017	The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells.
1/2017	CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.
12/2014	Cholesterol and breast cancer pathophysiology.
9/2014	Obesity, cholesterol metabolism, and breast cancer pathogenesis.
11/2013	27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.

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Erik R Nelson Research Topics

Disease

21	Breast Neoplasms (Breast Cancer) 10/2022 - 01/2010
18	Neoplasms (Cancer) 10/2022 - 07/2012
11	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2010
7	Hypercholesterolemia 01/2021 - 03/2013
5	Obesity 01/2021 - 09/2014
4	Osteoporosis 10/2017 - 08/2010
4	Prostatic Neoplasms (Prostate Cancer) 10/2017 - 07/2012
2	Inflammation (Inflammations) 01/2021 - 01/2021
2	Atherosclerosis 01/2019 - 10/2017
2	Ovarian Neoplasms (Ovarian Cancer) 01/2019 - 03/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Weight Loss (Weight Reduction) 01/2021
1	Necrosis 01/2021
1	Disease Progression 01/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2019
1	Triple Negative Breast Neoplasms 12/2016
1	Residual Neoplasm 12/2016
1	Brain Neoplasms (Brain Tumor) 10/2015
1	Dyslipidemias (Dyslipidemia) 12/2014
1	Bone Resorption 08/2012
1	Metabolic Diseases (Metabolic Disease) 08/2010
1	Postmenopausal Osteoporosis 08/2010

Drug/Important Bio-Agent (IBA)

15	Estrogen ReceptorsIBA 10/2022 - 01/2010
14	CholesterolIBA 01/2022 - 08/2010
12	27-hydroxycholesterolIBA 01/2022 - 08/2010
7	Estrogens (Estrogen)FDA Link 01/2019 - 08/2010
7	Selective Estrogen Receptor Modulators (SERM)IBA 10/2017 - 01/2010
5	LigandsIBA 01/2022 - 11/2013
5	Pharmaceutical PreparationsIBA 01/2021 - 09/2014
4	Liver X ReceptorsIBA 01/2022 - 11/2013
4	EnzymesIBA 11/2020 - 11/2013
4	OxysterolsIBA 01/2019 - 03/2013
4	Tamoxifen FDA LinkGeneric 10/2015 - 01/2010
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2022 - 01/2019
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2020 - 10/2017
3	Proteins (Proteins, Gene)FDA Link 01/2017 - 10/2014
2	Estrogen Receptor alphaIBA 10/2022 - 10/2015
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2018
2	Fulvestrant (Faslodex)FDA Link 01/2019 - 10/2015
2	Hormones (Hormone)IBA 10/2014 - 03/2013
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Estrogen Receptor Modulators (Antiestrogen)IBA 06/2020
1	LuciferasesIBA 06/2020
1	ChemokinesIBA 01/2019
1	Calcium-Calmodulin-Dependent Protein Kinase KinaseIBA 01/2019
1	ChromatinIBA 01/2019
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 03/2018
1	Paclitaxel (Taxol)FDA LinkGeneric 03/2018
1	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2018
1	Adenosine Triphosphate (ATP)IBA 03/2018
1	Sterol Regulatory Element Binding Protein 2IBA 01/2017
1	LDL Receptors (LDL Receptor)IBA 01/2017
1	Cadherins (E-Cadherin)IBA 12/2016
1	Polysaccharides (Glycans)IBA 01/2016
1	RAD1901IBA 10/2015
1	Aromatase InhibitorsIBA 10/2015
1	Transcription Factors (Transcription Factor)IBA 12/2014
1	Protein Disulfide-IsomerasesIBA 12/2014
1	afimoxifene (hydroxytamoxifen)IBA 12/2014
1	AndrogensIBA 10/2014
1	CopperIBA 10/2014
1	Copper Transport ProteinsIBA 10/2014
1	Disulfiram (Antabuse)FDA Link 10/2014
1	Androgen Receptors (Androgen Receptor)IBA 10/2014
1	Oxidoreductases (Dehydrogenase)IBA 11/2013
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 11/2013
1	Aromatase (CYP19)IBA 05/2013
1	bazedoxifeneIBA 05/2013
1	CytokinesIBA 08/2012
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2012
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2010

Therapy/Procedure

12	Therapeutics 01/2021 - 03/2013
2	Drug Therapy (Chemotherapy) 03/2018 - 12/2016
1	Retreatment 01/2021
1	Immunotherapy 01/2019
1	Neoadjuvant Therapy 12/2016